PI3K/Akt通路,PI3k/Akt pathway
1)PI3k/Akt pathwayPI3K/Akt通路
1.Influence of downregulated HER2 expression by Herceptin on the protein expression via PI3K/Akt pathway;Herceptin下调HER2表达后对PI3K/Akt通路蛋白表达的影响
英文短句/例句
1.The Role of PI3K/Akt Pathway in Radiosensitization of HeLa CellsPI3K/Akt通路在药物放射增敏中作用的机制
2.Ghrelin Inhibits Apoptosis Induced by Oxidative Stress in Adult Rat Cardiomyocytes, Throught the PI3K-Akt Signaling PathwayGhrelin通过PI3K/Akt通路抑制氧化应激诱导的成年大鼠心肌细胞凋亡
3.Study on the Effect of PI3K/Akt Pathway and Its Inhibitor LY294002 on the Pathogenesis and Treatment of Lung Cancer;PI3K/Akt通路及其抑制剂LY294002在肺癌发病机制及治疗中的作用研究
4.The expression of PI3K/Akt signal pathway and HIF-1α in gastric carcinomaPI3K/Akt信号通路及HIF-1α在胃癌中的表达
5.PI3K-Akt Signaling Pathway and Myocardial ProtectionPI3K-Akt信号通路与心肌保护
6.Correlation of PI3K/Akt Signaling Pathway to TumorsPI3K/Akt信号通路与肿瘤关系的研究进展
7.Endothelial Progenitor Cells and PI3K/Akt Signal Transduction Pathway内皮祖细胞与PI3K/Akt信号传导通路
8.The Effects of PI3K/Akt Signaling Pathway on Apoptosis Induced by H_2O_2 in PC12 Cells;PI3K/Akt信号通路在H_2O_2诱导的PC12细胞凋亡中的作用
9.The Relationship between Phosphatidylinositide 3-OH Kinase/Akt Pathway Activation and Drug Resistance in Human Ovarian Cancer;PI3K/Akt信号通路与卵巢癌耐药关系的研究
10.Functional Analysis of Phospholipase D3 in Insulin Stimulated Pathway of PI3K-Akt-GLUT4磷脂酶D3对胰岛素（PI3K-Akt-GLUT4）传导通路的调控研究
11.The Critical Role of RARγ in Cross-talk between PI3K/AKT and NF-κB Signal PathwaysRARγ在PI3K/AKT和NF-κB信号交互通路中的作用
12.Regulationary of PTEN/PI3K/Akt Pathway on Apoptosis of K562 CellsPTEN/PI3K/Akt信号通路对K562细胞凋亡调控的研究
13.Expression of PI3K/Akt signal pathway in acute myocardial ischemia急性心肌缺血损伤中PI3K/Akt信号通路表达的研究
14.The Study Progress about Human Herpesivirus-8 Infection and Phosphatidylinositol 3-kinase-Akt Signal Transduction PathwayHHV-8感染与PI3K/Akt/mTOR信号转导通路研究进展
15.Research Progress of PI3K/Akt/mTOR Signal Pathway and Ovarian CarcinomaPI3K/Akt/mTOR信号转导通路与卵巢癌研究进展
16.Application of PI3K/Akt and COX-2 signal pathway blockage in treatment of gastric carcinomaPI3K/Akt和COX-2信号通路阻断在胃癌治疗中的应用
17.Effects of inhibition of PI3K/Akt signal pathway by LY294002 on human gastric carcinoma SGC-7901 cellsLY294002抑制PI3K/Akt信号通路对人胃癌SGC-7901细胞的影响
18.PI3K-AKT Signaling Pathway Regulates TGF-β Signaling Pathway in Prostate Carcinoma CellPI3K-AKT信号通路对前列腺癌细胞中TGF-β信号通路调节作用
相关短句/例句
PI3K-Akt signal pathwayPI3K-Akt通路
3)PI3K/AKT/PTEN pathwayPI3K/AKT/PTEN通路
4)PI3K/AKT/mTOR signalingPI3K/AKT/mTOR通路
5)IGF-PI3K-Akt signaling pathwayIGF-PI3K-Akt信号通路
1.Recent evidence suggests that normal and exercise-induced cardiac growth are regulated in large part byIGF-PI3K-Akt signaling pathway.近年来,研究表明心肌的正常生长以及运动诱导的心肌生理性肥大,主要是通过IGF-PI3K-Akt信号通路进行信号转导。
6)PI3K/Akt signal pathwayPI3K/Akt信号通路
1.Prosaposin pro-tein was proved to activate thePI3K/Akt signal pathway,upregulate the phosphorylative activity of Akt at Serine 473,downregulate the expression of P27Kip1 gene,upregulate the expression of Cyclin D1 gene and then promote the G1/S tran-sition,and upregulate the expression of survival genes cIAP1 and cIAP2 and then prevent cell apoptosis.1 in NIH3T3阴性对照细胞株和过表达prosaposin的Psap-Myc in NIH3T3细胞株为模型,噻唑蓝(MTT)比色法检测prosaposin对细胞增殖的影响;Annexin V联合碘化丙啶(Propidium iodide,PI)法检测血清饥饿状态下prosaposin对细胞凋亡的影响;Western blotting检测PI3K/Akt信号通路中蛋白磷酸化水平的变化;Real-time PCR检测PI3K/Akt信号通路下游靶分子表达水平的改变。
延伸阅读
开辟通路开辟通路breachingkaiPi tonglu开辟通路(br eaching)在障碍区中排除障碍物以开辟通道的行动。工程保障任务之一。包括陆上开辟通路和水中开辟通路。目的是确保人员、车辆、舰艇、登陆输送工具等安全通过障碍区。中国战国时期，在进攻城池的作战中，已用人工清除鹿碧、铁羡黎等障碍物。明代中后期，采取了爆破法排除地雷、水雷。第一次世界大战时期，广泛采取了爆破法在地雷、铁丝网等障碍区中开辟通路。第二次世界大战时期，还使用炮兵、航空兵等火力开辟通路，严密组织火力、烟幕掩护开辟通路。开辟通路须运用各种力量，充分发挥工程兵的骨干作用;预先查明障碍物配系和敌火力控制等情况，做好开辟通路的各项准备;根据任务、时间、敌情选择开辟的方法，明确规定开辟通路的数量和宽度。使用人工和机械开辟通路时，还须周密组织火力与烟幕掩护，尽量利用能见度不良时实施。基本方法有爆破法、机械法和人工法。有时炮兵、航空兵、舰艇部队的火力也用于开辟通路。通常以扫雷滚、爆破器、探雷器和手工作业排除地雷、铁丝网;用推土装置和爆破装置排除壕、坑、桩紫等障碍物;使用扫雷舰艇、直升机和潜水员排除水中障碍物。在沾染区和化学障碍物中开辟通路须穿戴防护器材;排除电障碍物、火障碍物时须防止触电和烧伤。开辟通路时，根据情况，灵活运用各种手段和器材，采取秘密开辟与强行开辟相结合的方法实施。秘密开辟通常在火力准备前进行，强行开辟在火力准备开始后实施。通路开辟完毕，进行标示和伪装，并以火力加以控制。当开辟的通路被敌封闭后，重新组织开辟。随着障碍物的发展，障碍物设置能力的增强，开辟通路的任务将更加艰巨，对专业技术的要求更高;由于大量使用高效、遥控排除障碍物的装备器材，作业速度将提高。(陈运鸿)使用爆破器开辟通路李子亮摄
