In this article, we will explore the world of tissue inhibitors of metalloproteinases (TIMPs), which are essential in the regulation of metalloproteinases, a class of enzymes involved in the degradation of extracellular matrix components. We will discuss the role of TIMPs in inhibiting metalloproteinases, their therapeutic potential in various diseases, and their impact on tissue homeostasis. Additionally, we will delve into the development and application of TIMP-based inhibitors in various medical fields. Through a collection of English short sentences and example sentences, we aim to provide a comprehensive understanding of the inhibition of metalloproteinases by TIMPs and the significance of this process in various physiological and pathological contexts.
组织金属蛋白酶抑制物,tissue inhibitors of metalloproteinases(TIMPs)
1)tissue inhibitors of metalloproteinases(TIMPs)组织金属蛋白酶抑制物
1.Objective To comprehensively evaluate the effects of hepatitis B virus X protein(HBx) on the expressions of matrix metalloproteinases(MMPs) and tissue inhibitors of metalloproteinases(TIMPs),then explore the potential role of HBx on invasion and metastasis of hepatocelluar carcinoma(HCC).目的全面分析乙型肝炎病毒X蛋白(Hepatitis B virus X protein,HBx)对基质金属蛋白酶(Matrix Metallo-proteinases,MMPs)及组织金属蛋白酶抑制物(Tissue Inhibitors of Metalloproteinases,TIMPs)的影响,探讨其在肝细胞癌的侵袭转移中的可能作用。
英文短句/例句
1.Expression of Tissue Inhibitors of Metalloproteinase-1、2 in the Rabbit Ocular Tissues of Perforating Cataract;兔晶体穿孔伤后组织金属蛋白酶抑制物-1、2在外伤性白内障眼组织中的表达
2.Clinical Significance of Expression of Matix Metalloproteinase-9、3 and Tissue Inhibitor of Metalloproteinase-1 in Glomeruli of Membranous Nephropathy;基质金属蛋白酶-9、3和金属蛋白酶组织抑制物-1在膜性肾病肾小球中的表达及意义
3.Experimental Study about the Expressions of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in Acute Pancreatitis;基质金属蛋白酶-2及基质金属蛋白酶组织抑制物-2在急性胰腺炎中表达的实验研究
4.The relationship between the expression of MMP-9,its inhibitor TIMP-1 and angiogenesis in invasive ovarian epithelial carcinoma基质金属蛋白酶-9及基质金属蛋白酶组织抑制物-1与卵巢上皮性癌血管生成的关系
5.Expressions of Matrix Metalloproteinase 9 and Its Tissue Inhibitor 1 in Pancreatic Carcinoma;金属蛋白酶-9（MMP-9）及其组织抑制物-1（TIMP-1）在胰腺癌中的表达
6.The Expression and Intervention of Matrix Metalloproteinase and Tissue Inhibitor of Metalloproteinase in Remnant Kidney Rats;残肾幼鼠肾组织基质金属蛋白酶及其抑制物的表达与干预
7.Expression of Matrix Metalloproteinase-2 and Tissue Inhibitor-2 in Cervical Carcinoma;基质金属蛋白酶-2及其组织抑制物在宫颈癌中的表达
8.Effects of High Glucose on the Expressions of MMPs and TIMPs in Rat Glomerular Mesangial;高糖对大鼠系膜细胞基质金属蛋白酶及其组织抑制物表达的影响
9.Relationship between matrix metalloproteinase-8/tissue inhibitor of matrix metalloproteinase-1 and premature rupture of membranes基质金属蛋白酶-8及组织抑制物-1与胎膜早破的关系
10.Expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in plasma of patients with colorectal carcinoma结肠直肠癌病人血浆金属蛋白酶及其组织抑制物的表达及意义
11.Target screening for RNA interference of the tissue inhibitor of metalloproteinase-1 gent金属蛋白酶组织抑制因子-1 RNA干扰靶位的筛选
12.Quantitative Study of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in Aqueous Humor of Patients with Glaucoma;青光眼患者房水中基质金属蛋白酶2及金属蛋白酶2组织抑制因子的定量研究
13.Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases of Chronic Allograft Nephropathy;基质金属蛋白酶/金属蛋白酶组织抑制因子在慢性移植肾肾病中的表达及其意义
14.The Dynamic Expression of MMP-9/TIMP-1 in the Course of Airway Remodeling of a Mouse Model of Asthma;基质金属蛋白酶-9/组织金属蛋白酶抑制剂-1在小鼠哮喘模型气道重塑中的动态表达
15.The Expression and Significance of Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Endometriosis;基质金属蛋白酶-9及基质金属蛋白酶组织抑制剂-1在子宫内膜异位症中的表达及意义
16.A Study on Expression of Matrix Metalloproteinase and Tissue Inhibitor of Metalloproteinase in Colorectal Carcinoma;基质金属蛋白酶及组织基质金属蛋白酶抑制剂在大肠癌中的表达研究
17.Significance of Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Hepatocellular Carcinoma;基质金属蛋白酶-9、金属蛋白酶组织抑制剂-1在肝细胞癌中的表达及其意义
18.Effect of orthodontic force on the expression of MMP-1 and TIMP-1 in gingival crevicular fluid of human正畸力作用下基质金属蛋白酶-1及金属蛋白酶组织抑制因子-1在龈沟液中的表达
相关短句/例句
Tissue inhibitor of metalloproteinase金属蛋白酶组织抑制物
3)MatrixMetalloprotenase-2/Tissue Inhibitor of Metalloprotenase基质金属蛋白酶/基质金属蛋白酶组织抑制物
4)tissue inhibitor of metalloproteinase组织金属蛋白酶抑制剂
1.Tissue inhibitor of metalloproteinases(TIMPs)are the natural repressor of MMPs,the ratio between MMPs and TIMPs may be a significant target to reflect the activity and prognosis of RA.组织金属蛋白酶抑制剂(TIMPs)是MMPs的天然抑制物,MMPs/TIMPs两者比例可作为反映疾病活动程度及预后的重要指标。
2.Aim To investigate the mRNA levels of tissue inhibitor of metalloprot einase-1(TIMP-1),tissue inhibitor of metalloproteinase-2 (TIMP-2) in rat car diac fibroblasts by multiplex reverse transcription-polymerase chain reaction ( RT-PCR).目的通过建立多重反转录聚合酶链反应(RT-PCR)方法,旨在测定大鼠心肌成纤维细胞组织金属蛋白酶抑制剂-1(TIMP-1)、组织金属蛋白酶抑制剂-2(TIMP-2)的mRNA水平。
5)TIMP金属蛋白酶组织抑制剂
1.Objective:To determine the effect of acitretin on MMP-2 andTIMP-2 and to explore its treatment mechanism in the patients with psoriasis vulgaris.目的:确定基质金属蛋白酶-2(MMP-2)及金属蛋白酶组织抑制剂-2(TIMP-2)在寻常型银屑病发病中的作用及阿维A对其的调节作用。
2.Matrix metalloproteinases(MMP) and Tissue Inhibitor of metalloproteinases(TIMP) can regulate the degradation and synthesis of extracellar matrix(ECM), and participate in many physiogical and pathological processes in vivo.基质金属蛋白酶 (MMP)和金属蛋白酶组织抑制剂 (TIMP)调节细胞外基质 (ECM)的分解与合成 ,参与体内多种生理病理过程。
6)tissue inhibitors of metalloproteinases组织金属蛋白酶抑制剂
延伸阅读
金属蛋白酶抑制剂分子式：CAS号：性质：一类组成结构中含有一个或一个以上金属离子的蛋白酶，凡能抑制此类蛋白酶又不使酶蛋白变性的物质，都属于金属蛋白酶抑制剂。如，由田无链霉菌MD706-Y4产生的磷酰胺素(phosphoramidon)，由马组链霉菌产生的塔罗肽(talopeptin)等都是金属蛋白酶抑制剂。
